Often, Dr. Neubrander asks which diet is best or in which order you should add diets. The following article was written by Dr. Neubrander to solve this problem.
Note that diets are an individual thing, and there is no simple answer. A few general rules that will apply to most patients in most cases (with the main exceptions, of course!): I start first with the GFCF diet and observe the clinical benefits. The next diet is usually SCD, followed by diets that eliminate special foods (elimination and rotation), food chemicals, such as phenols, salicylates, glutamates, excitotoxins, etc. D. This can be followed by a “limited” low oxalate diet (not yet strict), body ecology diet or GAPS (bowel syndrome and psychology diet) diet. The last diet that many parents are switching to is a very “strict” diet with a low oxalate content. MAKE SURE THAT NO NO INITIATIVE ORDER & # 39; AND DIFFERENT CHILDREN WERE BETTER TO SWITCH ORDER. This is what parents and their doctors could do together, although more often parents do not experiment on their own, watching what works and what does not work for their child.
As stated, there are reasons why a child may need to skip the “next regular diet that will be added” to go further in the list. These “omissions” or “exceptions” are usually based on the child’s symptoms, the discussion is too large and too specific to be included in this commentary. Test and error is a proven method. Laboratory tests are very often misleading and confusing. In addition, laboratory tests are not always available for many different “mechanisms of action” that can be operational. Even if it was possible to conduct a laboratory test, because there are so many different laboratory tests to look at all the different mechanisms - IgE "true" food allergy, non-allergic "delayed" hypersensitivity IgG, difficulties with the destruction of peptides, gastrointestinal enzyme deficiencies, cytotoxicity , direct chemical reactions, toxic or intolerable reactions to food components or pollutants, etc. - it is financially impossible and impractical to do all this. Therefore, CLINICAL TEST - TEST FOR BEST LABORATORIES OF THE BODY, but only if it is done in a systematic and progressive way.
In general, without casein, a gluten-free diet helps more than 60% of children in the spectrum of autism in accordance with the data of ARI. Although such a diet has historically mocked our detractors as unproved, unhealthy and ineffective, as time stamps appear in respectable journals documenting this diet for a significant subset of children in the spectrum. The reasons discussed in the published papers, why this diet works, have their own spectrum, ranging from "unknown but definite" to "gastrointestinal" up to "immunological" reasons. A recently described but definite reason that milk can play a negative role in children in the spectrum is caused by a folate deficiency in the brain. In the “absolute” deficit syndrome, an autoimmune reaction occurs when the body produces antibodies against folate receptors found in the chloroids plexus, thereby blocking the body’s ability to regenerate folic acid molecules through the blood-brain barrier in the cerebrospinal fluid and extremely in neurons. It becomes obvious that every child does not have to meet the criteria that must be diagnosed with an "absolute" folate deficiency in the brain in order to suffer from similar negative neurological symptoms due to a "partial or incomplete" blockade of the same biochemical pathway. Studies of brain folate deficiency show that when milk is present, blocking antibodies are enhanced, when blocking antibodies are challenged in essence when milk is removed from a baby’s diet, and when milk is reintroduced, blocking antibodies rise again very quickly! Studies also show that the longer it is exposed to milk, the higher the level of antibodies. Of particular interest at the time of publication of this message (August 2011) is that out of 120 children we tested so far in our clinic for folate receptor autoantibodies, 2/3 of them (65.8%) were positive either to block, / or bind folate receptor autoantibodies. Even more interesting is that we can often do something to effectively treat the problem, sometimes even the category of "Wow-degree"
What is not entirely clear is that there are many different “mechanisms” for why certain foods can cause problems in different subsets of people who are similar to each other and have the same symptoms. Casein can be used as one example. Some patients cannot tolerate casein due to the OPIOID MECHANISM that causes the drug reaction. This opioid-like phenomenon is associated with the inability of “specific” enzymes that break down the key bonds that occur between molecules that hold certain parts of the casein molecule. [also certain parts of a gluten molecule]Therefore, if the patient lacks this specific enzyme, DPPIV ["DPP-four"], casein cannot be broken down into its lowest common denominator (individual amino acids, called “peptides”), and then remain in the form of polypeptides or “dipeptides”, which are then absorbed and subsequently “misread” by the body’s opioid receptors which they cross-react with opioids [morphine-like drugs]This “OPIOID REACTION” for casein / dairy products represents “ONE SPECIFIC MECHANISM” for a variety of mechanisms that may not be suitable for a particular subset of children. “ADENOSINE CONNECTION” - “OTHER SPECIFIC MECHANISM” in which dairy products from milk (not eggs), acting through the DPPIV path, block the effectiveness of methyl-B12.
“OTHER SPECIFIC MECHANISM”, why some children will do better without dairy products, is because the child may have “TRUE FOOD ALLERGIES”, for example, an IgE antibody response [accepted by all conventionally trained physicians]However, the “OTHER SPECIFIC MECHANISM”, why some children will do better without baby products, is that the child may have “FOOD SENSITIVITY / INTROLINES”, for example, an IgG antibody response [accepted by most alternative medicine practitioners but only a small percentage of conventionally trained physicians], “OTHER SPECIFIC MECHANISM” will include AN ANNERVAL CYTOTOXIC RESPONSE when cell nuclei are directly incubated with casein. When this is done, the kernels will be “angry” by acquiring a much more blue dye, and the kernels look just like the sky before a thunderstorm, and not the blue sky on a summer day. However, the "OTHER SPECIFIC MECHANISM" will include LACTIC TOLERANCE if the "other enzyme" than the one described above cannot break down the milk sugar. When this happens, undigested milk sugar bypasses the absorption in the small intestine and moves down to the large intestine, where bacteria and yeast say: “Hippie, beer and pretzel time!” And hold a party on the front lawn of the large intestine. Unfortunately, the overblown bacteria and yeast by-products are the production of hydrogen and methane gases, with the result that the child feels bloated with flatulence and possibly abdominal pain.
Many similar mechanisms occur with a child, which may be better on a gluten-free diet, for example, the opioid mechanism of DPPIV, the mechanisms of IgE and IgG, and the cytotoxic mechanism. ADDITIONAL MECHANISM comes into play with gluten, which is AUTOIMMUNE PHENOMENON, known as CELIAC DISEASE. In this disorder, the body forms an antibody against its own intestinal mucosa. Damage to the mucous membrane is damaged, and therefore the absorbing surface becomes compromised, which impairs the body's ability to absorb. This can be imagined by opening the hand to observe the fingers and joints, which we will define as absorbing surfaces. When antibodies destroy the surface lining, paint it by making a fist. Now compare the two - the first one has an amazing surface area, and the second one is very small. So it is with celiac disease.
A popular diet right now for autistic children is a specific carbohydrate diet (SCD). The "mechanism" when working in this diet is another enzyme deficiency - a certain class of enzymes that are expected to destroy starches or "two-component, two-molecular sugars." The food classification, known as “carbohydrates,” consists of individual biochemical units, known as sugars. [these are "biochemical sugars" that are not the same as the lay term "sugar"]These biochemical sugar molecules have common names, such as glucose, fructose and galactose. Biochemically, these individual units of biochemical sugars are called mono ["one"] saccharides ["sugar molecule"]When two of these individual sugar molecules are combined, they are now called dissacharides ["two" "sugar molecules"]When one glucose biochemical sugar molecule is combined with one galactose biochemical sugar molecule, the result is a disaccharide lactose, commonly known as milk sugar. When one molecule of the biochemical glucose sugar is combined with one biochemical molecule of fructose sugar, the result is a disaccharide, commonly known as “fruit sugar”. When one molecule of the biochemical glucose sugar combines with another molecule of the biochemical glucose sugar, the result is a disaccharide, commonly known as “starch”. It seems clinically that there is a subclassification of enzymes that are unable to destroy the "starchy" disaccharides [names like isomaltase - a disaccharidase; palitinase - a dissacharidase, etc]These types of disaccharidases are especially heavy in the intestinal tract. [remember "ase" added to the end of a word just means an enzyme that digests the similarly named substrate, eg lactase digests the substrate lactose, etc.]By simply removing these “significantly hotter disaccharides” from a child’s diet, the child can improve significantly.
Other diets include elimination diets based on "real allergy tests - IgE tests", "tolerance / sensitivity allergy tests - IgG tests", "cytotoxic sensitivity tests - lymphoblastic activation" or "chemical reactions to food substances", for example Feingold diet and other similar diets, “metabolic disorders,” for example, avoiding products containing such substances as phenols, disrupters of the sulfur path, tyramines, nightshade, oxalate diet, etc. Each of these diets may work due to individual mechanics mov or alternately due to the synergistic combination of mechanisms working together.
PLEASE NOTE that the ONE MOST VALUABLE LABORATORY TEST is a child’s special reaction to the administration, restriction, and then repeated administration of a potentially hazardous substance. Therefore, when in doubt, cut it out of a child’s diet and are clinically obsessed for results. Understand that removing an item may not produce clinical results that are easily observed. However, if you reintroduce food, symptoms or decomposition may occur.
The only real exception to the general principle outlined above is “big villains,” things that are known to be life-threatening, things like peanuts, shrimp, etc. These are real allergic reactions of IgE and can have serious consequences. if they do not comply. These substitutes should not be considered re-introduction only to find out whether the child has improved or can carry the substance or not. The problem is that if you re-enter, two things can happen. When first introduced again after a lack of food for a certain period of time, the body may not have an external reaction, although the body will lose what was a “temporary amnesic response” inside the body because it avoided food for a long period of time while it is set to serious reaction if food gets back within a relatively short period of time. The second thing that can happen is that the child can react to the first re-introduction of food and have a potential threat to anaphylactic life.
Remember that each child is different and that each diet is different. The best way to determine when to start and when to stop a diet will be different from one child to another. Therefore, I always recommend professional help in these matters. As a standard for my practice, if I believe that the result of starting a diet can be “very important” or have significant benefits or side effects, I recommend starting a diet at a time when no other variables are added or removed from the program for the child. The same general principle applies to stopping the diet.
No doubt diets are very upsetting. They are not the “American way”! Proper diet is not easy to find. And no diet is ever easy. He takes on the obligation of parents and changes the way of life of the family, which is one of the most difficult things for all of us - change! However, diets should be investigated by each parent, because when the right diet is found, many of the unpleasant symptoms associated with the spectrum of autism will completely or completely disappear ~! Good luck on your journey. We are here to help you in any way along the way.
James A. Neubrander, MD
